Associate Principal Scientist, Imaging

Job title: Associate Principal Scientist, Imaging in West Point, PA at MSD Company: MSD Job description: Job DescriptionThe Translational Imaging team at our Company's Research Laboratories in West Point, PA is seeking a talented Associate Principal Scientist to support the discovery and qualification of novel positron emission tomography (PET) tracers with their expertise in the application of radioligand binding assays. This Associate Principal Scientist will work in a collaborative research environment to support drug discovery programs across multiple therapeutic areas, with a focus on neuroscience and oncology.Responsibilities:Design, optimize and perform in vitro radioligand binding assays, including autoradiography and tissue homogenate binding assays, to assess the binding characteristics of radioligands to support PET tracer discovery and developmentAnalyze, interpret results and draw conclusions from experiments, and suggest, design, and pursue relevant experimentsGenerate reliable and reproducible data in a timely mannerPresent results and next steps at group meetings and project meetingsAccess and understand relevant scientific literature and apply theoretical framework to solving problems within scientific discipline in a timely manner.Work effectively with other scientists as part of a collaborative, multidisciplinary teamQualifications:Education:

• Master's (with 8+ years) or Ph.D. in biology, pharmacology, radiopharmaceutical sciences or related field and relevant work experience in the area of radiopharmaceutical discovery

Required Experience and Skills:Design, optimization, and implementation of radioligand binding experiments in tissue homogenateDesign, optimization, and implementation of autoradiography experiments on tissue slicesSectioning of frozen tissue for autoradiography experimentsAbility to independently design, execute and interpret in vitro radioligand binding experimentsAnalysis and interpretation of data from in vitro binding experiments using graphical nonlinear curve fitting software methodsTheoretical knowledge of ligand-receptor binding interactions and their application to drug discoveryProven track record of generating publication quality data and contributing to manuscript or patent preparation.Highly developed oral and written communication skills and keen ability to engage internal and external team members in collaborative researchSelf-motivated and resourceful with good interpersonal skillsAbility to independently manage workflow to see projects through from start to completionStrong interpersonal, verbal and written communication skillsWillingness and ability to work with radioactive materials including ³H, 18F, and/or 89Zr.Strong record keeping skillsDemonstrates a high level of attention to detailPreferred Experience and Skills:Experience with molecular biology assays such as Western blot, ELISA, etc.Immunohistochemistry and/or immunofluorescence staining experience#EligibleforERPCurrent Employees applyCurrent Contingent Workers applyUS and Puerto Rico Residents Only:Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please if you need an accommodation during the application or hiring process.As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.U.S. Hybrid Work ModelEffective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance OrdinanceLos Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring OrdinanceSearch Firm Representatives Please Read Carefully Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.Employee Status: RegularRelocation: Domestic/InternationalVISA Sponsorship: YesTravel Requirements: No Travel RequiredFlexible Work Arrangements: Not ApplicableShift: 1st - DayValid Driving License: NoHazardous Material(s): YESJob Posting End Date: 06/30/2025*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date. Expected salary: Location: West Point, PA Apply for the job now! Apply for this job